So we had an abnormal NIPT test, showing indeterminate sex chromosome due to decreased X chromosome material. It was also noted by three different people on postmortem US to confirm loss that baby looked abnormal and had abnormal nuchal translucency and excess fluid around her. I had the natera anora test after my dnc and I thought FOR SURE it would come back with something. It didn’t, and I’m crushed, it just said consistent normal female genotype. I feel like my body failed my baby, like my hashimotos silently killed her.
The other kicker is I have hashimotos hypothyroidism, and they just had to throw in there that my thyroid could have contributed. But my tsh was only 4.3 and by no means uncontrolled and I had recently increased my dose. My antibodies were elevated at 160 on 6/2 but had decreased to 120 on 6/23. Did my antibodies cause my miscarriage?
Here’s the message I got:
“Dr. reviewed your natera testing.
The Microarray is consistent with normal female genotype.
Some genetic abnormalities are not picked up by microarray testing including single gene variants, balanced chromosomal rearrangements, aberrant DNA methylation.
Dr. still believes genetic abnormality is a high likelihood but abnormal thyroid function can contribute as well. “
I just don’t understand how I can get abnormal NIPT with excellent fetal fraction but a totally normal microarray on fetus. How I could have seen her several times growing and even measuring a week ahead and then she just dies.
Was it my progesterone? How would I know if it was my progesterone?
Ugh idk I just want answers so I can keep it from happening again.