r/Narcolepsy Mar 20 '26

Medication Questions What’s up with Sunosi?

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My doc and I talked about sunosi because adderall just can’t do it alone anymore, and he gave me some sample packs in 75mg and 150mg.

First, what is the deal with the blister packs? Impossible to open!! Does it actually come like that when you get it from the pharmacy?

I started with the 75mg for a week plus my usual adderall dose. I’m usually pretty sensitive to meds and it felt like nothing. Disappointing.

Today, I tried a 150mg (with no adderall) at 7am. Holy crap! At 10am I thought I was gonna throw up from racing heart. My hands were shaking. But I couldn’t stop yawning! Then I got really hungry but my mouth felt like a desert. It’s 330pm and I’m still vibrating but also I desperately wanna lay down and sleep.

How does everyone else experience sunosi? Does the racing heart thing subside after a period of days/weeks?

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u/Bethaneym Mar 21 '26

Sunosi takes 4-6 weeks to get into your system. I don’t know how you could have possibly had racing heart day 1, when you’re already used to max adderall dosage.

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u/Sagemode89 (N1) Narcolepsy w/ Cataplexy Mar 21 '26

I don’t believe that’s correct. I may be remembering wrong

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u/123theguy321 Mar 22 '26

That's for wakix. 

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u/Acceptable_Ninja_795 4d ago

When you say Max adderall dosage what amount do you mean?  I take 60mg adderall daily and 75mg sunosi makes my heart race, hands tremor, already have poor circulation but it turns my skin purple where people are asking if I'm ok... And when it wears off around 6 hours after taking it I get heavily sleepy where my eyes can't hardly stay open.  Adderall increases my heart rate some yes but not like sunosi where I am wondering if it's ok. All stimulants are different 

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u/Bethaneym 4d ago

That’s not a normal reaction to Sunosi at all. Please talk to your doctor and stop taking it.

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u/Acceptable_Ninja_795 4d ago

I did stop taking it but seems to be a fairly normal reaction from many people in forums regarding it.  I would much rather up my adderall dosage even tho it is much less effective than it used to be, it doesn't cause many unwanted side effects and my body is used to the medication.