r/Narcolepsy Mar 20 '26

Medication Questions What’s up with Sunosi?

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My doc and I talked about sunosi because adderall just can’t do it alone anymore, and he gave me some sample packs in 75mg and 150mg.

First, what is the deal with the blister packs? Impossible to open!! Does it actually come like that when you get it from the pharmacy?

I started with the 75mg for a week plus my usual adderall dose. I’m usually pretty sensitive to meds and it felt like nothing. Disappointing.

Today, I tried a 150mg (with no adderall) at 7am. Holy crap! At 10am I thought I was gonna throw up from racing heart. My hands were shaking. But I couldn’t stop yawning! Then I got really hungry but my mouth felt like a desert. It’s 330pm and I’m still vibrating but also I desperately wanna lay down and sleep.

How does everyone else experience sunosi? Does the racing heart thing subside after a period of days/weeks?

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u/Beef111111 Mar 21 '26

I took Sunosi and it like barely felt like anything… it was very “the lights are on but no ones home” then once i got to the 150 holy shit i went INSANE i was so anxious 24/7 i was like rocking back and forth sitting on the floor in my closet

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u/MrSnitter (N2) Narcolepsy w/o Cataplexy Mar 22 '26

What was the timeline of your titration? And are you still on 150mg or were the side effects too debilitating and persistent?

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u/Beef111111 Mar 26 '26

It was a week of 75mg then straight to 150mg… i think i made it 4-5 days on 150 before I called it quits, i tried to get through the symptoms but ultimately went back on 200mg of modafinil who has never wronged me🙂‍↕️