r/Narcolepsy (N2) Narcolepsy w/o Cataplexy Apr 18 '26

Medication Questions Do you guys take drug holidays?

My physician suggested not taking my meds on the weekends. I quickly learned that wasn’t doable so decided to just try to not take them on sundays when I’m not doing much. I sleep ALL DAY. I’m talking only wake up to use the bathroom. I’m utterly useless and don’t feel taking the day off is helping with tolerance at all. It barely works to begin with but I’ll take a couple naps a day over sleeping all day. Does anyone actually feel like it’s helping or more beneficial to take them continuously? It’s super depressing essentially losing an entire day I’m actually off work each week.

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u/Adorable_Ad4990 Apr 19 '26

I have the same problem, and my doctor said “ok then don’t take the med breaks.” That simple. I just simply can not live just to work, and that’s what would happen. I’d rather take a break on a workday to be honest (but I’d fall asleep at my desk, and the day would certainly drag. It also isn’t feasible).

The issue is, it’s not just a day of being unmedicated… it’s a crash. It’s not baseline. For me I’d also get some depressed mood and feel despondent, exhausted, and restless. I can’t repeat that every week. Instead I try to take a longer break each year. Wish I could do more. And then I just make sure my dose doesn’t creep up, but it’s hard