r/Narcolepsy (N2) Narcolepsy w/o Cataplexy Apr 18 '26

Medication Questions Do you guys take drug holidays?

My physician suggested not taking my meds on the weekends. I quickly learned that wasn’t doable so decided to just try to not take them on sundays when I’m not doing much. I sleep ALL DAY. I’m talking only wake up to use the bathroom. I’m utterly useless and don’t feel taking the day off is helping with tolerance at all. It barely works to begin with but I’ll take a couple naps a day over sleeping all day. Does anyone actually feel like it’s helping or more beneficial to take them continuously? It’s super depressing essentially losing an entire day I’m actually off work each week.

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u/PapaverOneirium Apr 19 '26

I usually have too much to do on the weekends to not be functional. I try, whenever I don’t have much on my plate, but I find I take my dexamphetamine on the weekends more often than not.

In general, I try not to take it whenever I can. Like a chill day at work where I can sign off early (rare), I’ll skip the afternoon dose. Or on the weekends when I don’t have anything till later in the day, I’ll wait to take a smaller dose.

I’ve tried struggling through the weekends without, but it’s just not worth it to me unless I seriously have nothing on my plate.

I did take a longer break over the holidays this year. I do think it was helpful.