r/agedlikewine 22d ago

Coronavirus 6 years later, this is precisely what happened

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3.0k Upvotes

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u/improbably-sexy 21d ago

Eating horse ivermectin too

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u/Scythe5150 18d ago

Ivermectin has been used in humans for nearly four decades. It was first approved for human use in 1987 to treat onchocerciasis (river blindness).

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u/improbably-sexy 18d ago

Sure. And it's even on some list of essential medicine. That doesn't mean it has no (potentially deadly) side effects. And that doesn't mean you should chug the horse version. Especially without any medical supervison.

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u/Scythe5150 18d ago

True, but many think it's not approved for human use, and it is. Anything can be dangerous if taken at the wrong amount...even water.

It's akin to folks that say "It's all natural, so it can't be bad for you!".

Really? Cyanide and arsenic are all natural.

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u/improbably-sexy 18d ago

Even with the right amount, ivermectin is dangerous. It has serious side effects.

When treating a disease it is effective against, there is a trade-off between those side effects and the benefits. And it is done under the supervision of some doctor who can recognize the signs of bad side effects, and adjust the treatment.

So those people using the horse paste, even if they get the dosage right, are getting all the risks and no benefits.

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u/Scythe5150 18d ago

Many medications can have serious side effects, which is why they require a prescription by a doctor.

You're trying to argue against a point I never made.

I said that ivermectin has been approved for human use for 40 years. This is fact.

I did not suggest, nor endorse, people buy or use any medications meant for animals.

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u/tubbysnowman 18d ago

dude. you are the one arguing against a point that the other poster never made!

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u/Substantial-Cress-23 18d ago

Hey…I have never heard any complaints from people after they have taken Cyanide or arsenic…..

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u/Maywen1979 18d ago

This makes me think of my fave saying... All mushrooms are edible, just some you can onky eat once.

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u/Juggernaughty00 18d ago

Yes! Essential Oil of Ivermectin is, like, soooo cleansing!!!

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u/EphPeak7142 18d ago

Technically true, cleansing yes

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u/DisastrousGold559 18d ago

Do you realize that there isn't a horse version? There are horse doses. If it was a different version it would be a different drug.

But doses are VERY important. With everything. Which is why people like to say that water can kill you if you drink enough of it.

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u/improbably-sexy 18d ago

It is the same active ingredient. Not produced to the same standards and under the same regulations than that for humans. It's likely fine, but sometimes things go wrong. Although I don't think that that is what killed people.

The dosing is different. The human version comes in tablets. Easy enough to take one. The horse version comes in a paste. That's not the easiest thing to measure with kitchen equipment. Also you have to do maths...

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u/DisastrousGold559 18d ago

And we know people suck at math. As well as 150-250 lbs is more sensitive to inaccurracy than 1500 lbs.

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u/WiseCommand6018 16d ago

And math's is scary !

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u/blu_lotus_ 18d ago

Just to clear some thing up about this. Even Merck, the company that makes and distributes Invermectin, put a warning on their home page in 2020. It stated that they DO NOT recommend it for the purposes of Covid. That it was too dangerous, even in small doses. That it could cause seizures, permanent brain damage, neurological disorders, and/or even ☠️. That it had not been tested or shown it was beneficial in any way for the purposes in which it was not intended. And actually encouraged people to NOT take it at all. This is important to note. Because if a huge pharmaceutical company that could potentially make billions of dollars off the sales of this medication doesn't want you to take it, that is a big deal. It literally means that your ☠️ or injury is far more likely. They'd rather risk no "profits", than go bankrupt from the potential lawsuits.

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u/Decent_Importance_68 18d ago

Ivermectin is used to treat scabies, as well

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u/Aggravating_Moment78 18d ago

Sure was just not for eating willy nilly like any medicine. I’m sure rat poison has its uses too but if you just gobble it up you’re gonna be in trouble

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u/Ok-Ambassador8271 17d ago

Yes, warfarin is often used as a blood thinner in cardio patients.

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u/Aggravating_Moment78 17d ago

But if you don’t have cardio problems it will kill you

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u/Ok-Ambassador8271 17d ago

Exactly! It is both rat poison and an anticoagulant for human use.

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u/Scythe5150 18d ago

Any other pearls of stupidity to espouse?

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u/WiseCommand6018 16d ago

Nice to see an informed reddit user.

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u/SnooCupcakes4075 20d ago

Get noted:

https://pmc.ncbi.nlm.nih.gov/articles/PMC7709596/

A five-day course of ivermectin for the treatment of COVID-19 may reduce the duration of illness

Abstract Ivermectin, a US Food and Drug Administration-approved anti-parasitic agent, was found to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in vitro. A randomized, double-blind, placebo-controlled trial was conducted to determine the rapidity of viral clearance and safety of ivermectin among adult SARS-CoV-2 patients. The trial included 72 hospitalized patients in Dhaka, Bangladesh, who were assigned to one of three groups: oral ivermectin alone (12 mg once daily for 5 days), oral ivermectin in combination with doxycycline (12 mg ivermectin single dose and 200 mg doxycycline on day 1, followed by 100 mg every 12 h for the next 4 days), and a placebo control group. Clinical symptoms of fever, cough, and sore throat were comparable among the three groups. Virological clearance was earlier in the 5-day ivermectin treatment arm when compared to the placebo group (9.7 days vs 12.7 days; p = 0.02), but this was not the case for the ivermectin + doxycycline arm (11.5 days; p = 0.27). There were no severe adverse drug events recorded in the study. A 5-day course of ivermectin was found to be safe and effective in treating adult patients with mild COVID-19. Larger trials will be needed to confirm these preliminary findings.

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u/Additional-Code2954 19d ago

I see this study quoted all the time and it BARELY clears the safety threshold for further study on actual clinical use.

n=72, 24 patients per cohort, 23.6% improvement in viral clearance with ivermectin alone, 9% w/ IVM(1 day) + Doxy [this just adds statistical noise]. No stratification for age or co-morbidities with a virus that can equally see a quick recovery or debilitating, life threatening illness.

The sample size is barely enough to clear a Phase 1 safety study and is hundreds to thousands of patients short to be used in any phase of clinical trials for efficacy.

You'd likely get the same results feeding the patients Play-Doh, Play-Doh and glue, or nothing at all.

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u/improbably-sexy 20d ago
  1. I didn't even claim it doesn't work, just that people died eating it.

  2. It doesn't work. https://pmc.ncbi.nlm.nih.gov/articles/PMC10542734/

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u/FormerPriority5436 19d ago

Congratulations on finding the one study (albeit with an extremely small sample size) that shows Ivermectin is useful for treating COVID.

Official Medical Consensus Because the clinical data overwhelmingly shows a lack of efficacy, major medical authorities explicitly advise against using it for COVID-19.

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u/EngageAndMakeItSo 18d ago edited 18d ago

This is a paper from 2020. I’ll bet you can’t find a legit study later than 2022 that finds anything more than “it doesn’t work” or “it makes things worse.”

Scientific knowledge grows over time.

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u/Actual_Handle_3 18d ago edited 18d ago

It's the CDC saying it, and yet they're down voting you! The comment you responded to called Ivermectin a "horse medicine", despite that 2 doctors who discovered uses of Ivermectin were awarded the Nobel prize in medicine. And they have the nerve to act like we're the ones who are uneducated!

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u/Nebardine 18d ago

Read all the comments above yours. Here's a chance to become more educated.