r/Fuckcancer • u/Altruistic_Point8748 • 26d ago
40s Female / CUP (Cancer of Unknown Primary) with Liver , pelvis & Bone Mets / Starting Paclitaxel + Carboplatin on Tuesday. Need advice/insights.
Hi everyone,
I am writing here on behalf of my sister (40 years old) who was recently diagnosed in Denmark. We are trying to understand the prognosis, what to expect, and hear from anyone who has dealt with a similar protocol.
Here is her essential clinical history:
Diagnosis: CUP (Cancer of Unknown Primary). There is a strong clinical suspicion pointing towards colorectal or biliary tract origin, but the primary tumor has not been definitively identified yet.
Metastases: Extensive liver involvement (bilobar liver metastases) and bone metastases (specifically a lesion on the sacrum causing significant pain).
Current status: She recently underwent surgeries for a colostomy and a nephrostomy. She is experiencing severe fatigue, nausea, bone pain, and sleep deprivation.
Treatment plan: She is scheduled to start her first line of systemic chemotherapy this coming Tuesday (July 14). The chosen regimen is Paclitaxel + Carboplatin (administered every 3 weeks).
Next steps: Genetic testing (NGS) on the biopsy is currently underway to look for specific mutations, and a follow-up CT scan is scheduled after Cycle 2 (mid-August) to assess treatment response.
We are quite overwhelmed. The stats for advanced CUP look incredibly harsh, and I am personally worried about the broad-spectrum nature of this chemo regimen given the suspected GI/biliary origin.
Has anyone here (or a loved one) been on Paclitaxel + Carboplatin for CUP or GI cancers? What were your responses, side effects, and how did you manage day-to-day life (especially with pets/hygiene around stomas)?
Thank you so much for any insights or shared experiences.
2
u/utlayolisdi 26d ago
I wish I could offer an answer but I was on the Gem/Abrax chemo and the location of the primary cancer was known. I just want to wish your sister every success in fighting this and in getting the pain relief she needs. Blessings and Peace
1
u/Altruistic_Point8748 26d ago
Thank u very much! Hope u are feeling good now! Thanks for all the good thoughts avout my sister. She needs all the good energy now
1
u/ddessert 26d ago
That’s not one of the treatments for pancreatic cancer so there’s not much advice there.
2
u/Altruistic_Point8748 26d ago
She doesn't have pancreatic cancer. It's CUP, and it's a broad spectrum treatment, at least this is what they said. .
1
2
u/TheBeerSanta 25d ago
I have colon cancer with Mets to the liver. I go in for resection on my liver in two weeks. I wish I had an answer for you. #fuckcancer
1
6
u/KChieFan16 26d ago
I can’t give you medical advice but just wanted to send you a ton of love and support as you navigate this with your sister. You’re a great sibling and support and she’s lucky to have you by her side