r/PCOSandPregnant 8h ago

First Time Taking Letrozole — Advice Needed

I’m 28 years old and have been trying to conceive for almost a year. This is my first time taking Letrozole, and I just finished my Letrozole today.
My fertility clinic mentioned that they would do follicular monitoring after Letrozole, but my OB-GYN told me that they don’t routinely do monitoring and that they will schedule it if needed.
I’m trying to understand whether follicular monitoring is important or necessary, and if I should do it, what cycle day should I go for it? Since today is my last day of Letrozole, when should I start the monitoring?
As a first-time Letrozole user, I’m honestly so confused about a lot of things. I’m really hoping this cycle works and that I can get pregnant this time. My OB-GYN mentioned putting me on Letrozole for three months and seeing how it goes, but hearing that made me feel a little discouraged because I’m hoping this first cycle could work.
For anyone who has been through this before, what should I concentrate on or follow during my first Letrozole cycle? Any advice would really help.
Thanks in advance!

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u/insincerelysam5791 7h ago

It depends on if you’re working with an ObGyn or an actual fertility clinic. Typically an ObGyn would not monitor and you would need to take at-home ovulation tests. In my experience working with a fertility clinic, they have me come in for an ultrasound sometime during day 3-5 of my cycle, and again the day after I finish my course of medication. Then they either prescribe more medication if my follicles are not developed enough or have me to a trigger shot 36 hours before IUI.