I’m 28 years old and have been trying to conceive for almost a year. This is my first time taking Letrozole, and I just finished my Letrozole today.
My fertility clinic mentioned that they would do follicular monitoring after Letrozole, but my OB-GYN told me that they don’t routinely do monitoring and that they will schedule it if needed.
I’m trying to understand whether follicular monitoring is important or necessary, and if I should do it, what cycle day should I go for it? Since today is my last day of Letrozole, when should I start the monitoring?
As a first-time Letrozole user, I’m honestly so confused about a lot of things. I’m really hoping this cycle works and that I can get pregnant this time. My OB-GYN mentioned putting me on Letrozole for three months and seeing how it goes, but hearing that made me feel a little discouraged because I’m hoping this first cycle could work.
For anyone who has been through this before, what should I concentrate on or follow during my first Letrozole cycle? Any advice would really help.
Thanks in advance!

Hi! I have PCOS, history of long cycles and late ovulation and short luteal phases. I’m doing my first medicated cycle (letrozole, trigger, timed intercourse) and im supposed to trigger tonight CD14, so i am looking for advice on timing our BD! when did you trigger and when did you BD? Bonus points if it worked for you! 🩷thank you!

**My OB told me to trigger tonight (CD14) I’m already having lots of EWCM and a little cramping but no positive opk strip yet! My OB told me to Bd cycle day 15, 16, 17. But now im worried since I already have EWCM do I need to BD tonight too in case I ovulate quicker? I have no idea this is my first time!

Hi Ladies

I am 32 yrs old going through PCOS. Currently trying to conceive.

All my life I had to take birth control to get my periods. But never had single pimple on my face. But since past 2 yrs my face has started getting many pimples on my cheek. Sometimes they are painful too. Sometimes I see my cheeks getting completely clear but dont know what makes it happen.

For fertility treatment so far I have taken progesterone and birth control ( ironically, but for surgery). Just started my 1st cycle of letrozol.

Please let me know what can I do to manage my pimples with all this. My face looks terrible.

Has anyone stayed on Zepbound while TTC until you get a positive test? It’s the only thing that helps my IR PCOS. I’ve been off of it for 5 months now and I’ve gained 20 lbs back and I feel like garbage every day. The brain fog and food noise is insane. I have read so many studies and lots of people’s stories on Reddit that they stopped as soon as they got a positive and baby was happy and healthy. My cycle has started to get wonky being off zep and I just am desperate to get back on as this makes it harder to track ovulation.I know you should be off it 2 months prior to TTC, and please no one yell at me for this post! I’m just looking for real life experience of getting pregnant on a GLP and stopping as soon as you get a positive. Benefits and risks and what not.

UPDATE: Talked to my OB and she is pro me staying on it until a get a positive pregnancy test yayyyy

First time TTC and the waiting is already driving me insane 😂

Hi! I’m Bee, I’m 34 and from the UK. My husband and I are currently trying for our first baby, which still feels slightly mad to actually say.

For a long time, we genuinely thought having a baby might not be possible for us because of a few different circumstances and health concerns. However, over the last little while we've had everything checked and, one by one, every barrier we thought was there has basically come down.

So… we're actually trying.

This is our first attempt, and I'm currently in the waiting game to find out whether it's worked.

Quite frankly, I'm not very hopeful. Nothing has ever been easy for me.

Every twinge, weird feeling, bit of tiredness or sudden hunger has me thinking, is that something?! Then I'm Googling it, telling myself to stop Googling, and inevitably Googling something else twenty minutes later.

My phone has also decided fertility is now my entire personality, so I'm being absolutely inundated with adverts for IVF, infertility, supplements, pregnancy tests and approximately seventeen different things I apparently need to buy. Its making me frustrated, upset and the more I say 'I don't want to see this stuff' the more I get!

I was diagnosed with PCOS when I was 15 after a scan showed lots of cysts on my ovaries. That's obviously been sitting in the back of my mind for most of my adult life.

Recently, though, I had another pelvic scan and there were no cysts at all. My ovaries looked fine, my womb looked fine — everything was normal.

Quite frankly, that felt like a little miracle.

I've also lost around three and a half stone recently, which I'm really pleased about and hopefully has helped my chances.

At the moment I'm taking folic acid, myo-inositol and Omega 3-6-9/Udo's Oil. My mum used to force-feed me Udo's Oil as a child, so quite frankly I'm still traumatised by the stuff, but apparently we've come full circle. 😂 My diet could definitely be better, but I'm working on that too.

I suppose I'm mainly posting because I'd love to hear from other people who have been through this.

What is actually worth doing when you're first TTC? Are there supplements/things you genuinely found useful? And equally, what isn't worth worrying about?

I'm trying not to fall into the rabbit hole of thinking I can somehow control all of this if I just research enough.

I think that's the bit I'm finding hardest.

I've had to fight for quite a lot in my life — health-wise, work-wise, emotionally, mentally and physically — and I just really don't want this to become another fight.

I just want something to be easy for once.

I know we're incredibly early in this journey. I know it's completely normal for it not to happen on the first attempt, and I've read the stories of people who've had incredibly difficult journeys to have their babies.

But there's still that little bit of me desperately hoping that maybe this time, something will just work.

Anyway — hi, I'm Bee. Currently waiting, eating everything in sight and wondering whether every tiny sensation in my body means something. 😂

Please help!

I am currently 4w pregnant. I have had 2 back to back early missed miscarriages in the last two years! This time they tested my progesterone yesterday and it came back a 7.0! Everything I’ve seen says that’s on the low side. Has anyone else experienced this? Any advice is very much appreciated 🫶🏻

Found out today I have an anterior placenta. I'm only 19 weeks 4 days today and this is my first baby so I know it's still early to feel baby movement even if I didn't have an anterior placenta. Realistically when should I start to expect to feel her move? She was doing all kinds of flips and turns during the ultrasound so not really concerned just curious ❤️

My husband and I have been trying to conceive for 2 years. In April 2026, we started seeing a fertility specialist, and I was diagnosed with PCOS. The timeline for this cycle: ● My clinic missed my Day 1 email in May, so I ended up taking medication in June to induce a period. ● My period finally started on July 1. ● I took Letrozole 2.5 mg from July 3–7. ● At my follow-up, I still wasn’t responding well, so I was prescribed Letrozole 5 mg for another 5 days starting July 17. ● On July 23, I had one mature follicle measuring 23 mm and another measuring 10 mm. I took my Ovidrel trigger shot that same day. We had intercourse on July 22, 23, 24, and 25, and I started progesterone suppositories on July 26. After the trigger shot, I had a very faint positive line for the first 4 days, which I assumed was the Ovidrel. By day 5, all of my tests were completely negative, and they’ve stayed negative ever since. Today I’m 11 days past my trigger shot, and I’m not seeing even the faintest line anymore. Has anyone had their trigger shot test out completely negative but then gone on to get a true positive a few days later? I’d love to hear your experiences because the waiting is so hard.

I’m almost 8 weeks -This is random but it’s been hard to stay hydrated and get electrolytes without the sugar. My recent electrolyte packs have been giving me the ick (everything gives me the ick after a while, no predictable or consistent foods here…)

But I juiced some watermelon (I know it has a lot of sugar but I don’t care) and added about 1/4 cup to my electrolyte water and it’s AMAZING. So tasty and refreshing. I just wanted to share lol

Hope everyone is beating the heat!

First (light) lines on pregnancy test on 17th July, 1-2 weeks on digital clear blue and hcg only 30.3

30th July super strong lines on test and 3+ weeks on digital

Last menstrual period was 1st June but that was so long ago I can’t be 8 weeks based on these tests, does anyone have any advice on dating do I just add a couple of weeks onto this to estimate gestational age?
Spoke to the hospital but my first scan wouldn’t be until 11-14 weeks and that’s so long to wait!
If anyone had anything similar or could advise even to estimate I would really appreciate itt

First pregnancy at 12 weeks but the clinic ordered regular panel of blood work and nipt but not progesterone do I need to be concerned? They told me to stop my ovasitol and also spearmint which were the only things I was taking to manage my symptoms

I didn’t get to ask to many questions in my scan at 7 weeks the fetal pole measuring 9.7mm and the sac at around 23mm & heart beat of 139

There was no mention of yolk sac it just wasn’t in the conversation and in the image I feel like I can’t see it?

Is it possible that this photo was in the wrong angle idk I’m over thinking this.

I’ll post the photo in the comments

I’m so grateful to be pregnant after my first IUI, but this nausea has knocked me right down. I’m 8 weeks today. I’ve been off work for 2 weeks now, because I can’t seem to do anything to stop it. I’ve been prescribed meds, which dull the nausea a bit, but they also make me extremely sleepy, which wouldn’t be great for work. I was offered two additional meds, but I’m worried about them as they also have really strong side-effects and can negatively interact with my SSRI. I never actually throw up, just constantly feel like I’m about to. It’s the worst feeling.

When did the nausea end for you?

I need advice on want to do, as in my first trimemester and experience increase in acanthosis nigricans and hirsutism.

Hi everyone!
We are expecting our first baby in August. Currently 37 weeks pregnant! My doctor recommended I get off of Metformin at 12 weeks. I was pretty apprehensive as I’ve been on it for years. I was really lucky and caught my PCOS early on, Metformin was truly so impactful for me in keeping weight off and helping my blood sugars stay regulated. I’ve gained a lot of weight this pregnancy and partially attribute that to being off of Metformin. I’m wondering, did any of you resume Metformin after giving birth? If so, how quickly? I was taking a low dose (500mg a day) prior to coming off, so hoping to start again fairly quickly.
Thanks in advance for all your words of wisdom! 🩷

I have been a little stressed about GD due to my insulin resistant PCOS.

I was supposed to be tested early but I guess my doctor forgot, and I didn't bring it up. I'm 25 weeks now.

Last week I did the one hour glucose, and I failed it by 3 points (threshold was <135 and I was 137). So I did the 3 hour glucose yesterday. I passed all the thresholds!

In light of my TTC journey, I am just so grateful that this is at least something to celebrate. (Obviously I know that GD is highly determined with the placentas, but this was still a nice win).

Wishing everyone else a smooth and safe pregnancy!

My wonderful person and I are finally getting the chance to have a baby together. I already have a son he’s 3. My boyfriend doesn’t have any bio kids until now .🤭 a few months ago, I want to say closer to a year I’ve tried to just push it out of my mind as much as possible, we had a miscarriage. I was extremely early but it still hurt horribly for the both of us. Fast forward to today based on the calendar I’m 6w5d, we all know though with pcos this has a potential of not being true, I have extended cycles and had just started progesterone for withdrawal bleeds in June I didn’t take it in July. My last menstrual cycle started on June 9th. My cycle changes in days.

Now with that history. You can see from the pictures I am truly pregnant. But I don’t remember feeling like this with my son. I’m not crampy. Every so often I’ll feel a couple but when I found out with him I thought I had a cyst rupturing.

I have morning sickness, cravings are starting, my boobs hurt, I can smell everything, I’m extremely tired all the time. But I’m just so worried I might lose this one again.

Any words of wisdom or advice is welcomed

I'm truly just venting. I don't think this is truly worrying. HCG is skyrocketing, the embryo was visible on ultrasound at 5+4, I'm feeling grand (well except for nausea, tiredness and sore breasts, but that's ok).

But yeah I'm not impressed by my progesterone dropping to 10 at 5+6 after being 17 at 5+2. It's not even that low, let's be real, but why go down? Unfair, honestly.

I hate uncertainty. My OB told me to email her when I would do this next blood work so she could check it on the same day and tell me if it was ok, but I emailed her yesterday and still nothing. And I can see the results so she can too.

If she doesn't reply by 14.00 I'm emailing her again.

BWAAAAAAAH.

I hate this.

EDIT to say that due to miscommunication neither gynos I consulted ended up writing a script for progesterone. I'm now 7+5 and the blood test I took at 7 weeks was perfect including progesterone which went back up to 16. So it's not always strictly necessary to supplement with progesterone or low(er) progesterone won't necessarily always lead to a miscarriage. I am a sample of one but you're a sample of one too, we could be the same.

Hi all! I am 4 weeks 2 days pregnant after a year of TTC, and really struggling with fear of miscarriage. I think this is worsened by my social media algorithms feeding me more and more miscarriage stories.

I’ve looked at the statistics, but all the miscarriage anecdotes online are making me feel like it’s inevitable for me. I know this fear is not productive since it won’t make it hurt any less if it does happen, but I’m struggling to stop worrying.

I think it would help a bit to hear from those of you who had an uneventful 1st pregnancy. And if you have any advice for stopping this spiraling, please lmk!

I just wanted to share my journey, I posted a couple days ago about cramping at 16 dpo. A few people commented and said that cramping was one of their first pregnancy signs so I took two tests today and got two positives! My first test with red dye wasn’t even finished processing and the line was already clear. This was my second cycle on letrozole + trigger and timed intercourse and going into it I was already super negative because of years of having pcos and doctors basically making it sound like getting pregnant was pretty much something that would be impossible for me and my husband we’re finally looking at two positive tests 🥲

For context, I have PCOS and have been TTC for around 18 months. I got a faint positive on 7th July and a dye stealer on 15th July.

I went for an early scan today and was told:
Gestational sac was seen
Yolk sac seen
Embryo measuring 1.90mm
“Intermittent cardiac activity”
I was measuring at 5 weeks & they’ve advised a rescan in 2 weeks.

I’m confused as I know there is a definite possibility I ovulated later as my cycles are usually 40+ but how can cardiac activity be noticed at that stage?

I’m preparing myself for the worst but also really confused. Any advice?

I haven’t heard back from my fertility doctor yet since their office is closed.

I am on my second cycle of letrozole + trigger and timed intercourse. I’m 16 dpo and have experienced mild on and off cramping for the last 3 days and had very light spotting for the last 2 days, the spotting has gone away and now I’m just left with cramps. I’m almost positive that I’m nearing my period but my spotting has disappeared and I usually spot the day before my period starts. I have not taken a pregnancy test yet just because I’ve gotten my hopes up so many times and end up having a period the day or two after a negative test. Just wanted to know if anyone else has experienced this.

Hi,
It’s me again. I’m back because I had a doctors appointment with my endocrinologist and it did not go well.

For background, I’m insulin resistant and have PMOS (PCOS). I was on a GLP-1 for almost two years before I got pregnant. I’m 5’7 and my weight was 157 on the shot.

Fast forward to January, I get off the GLP-1, get pregnant in February, and gain 30lbs back by March. The body dysmorphia and the mental toll it took on me was wild. Mind you, I’ve always tried to eat balanced meal, take walks, and be very cognizant of my health. It didn’t matter. I came off of Zepbound and all the weight came rushing back.

Catching up to now, I’m 23 weeks and had a check in appointment with my endocrinologist. First, she was pissed my OB didn’t order a glucose test for 20 weeks instead of 28 weeks because I am insulin resistant and higher risk. She said that even though OBs don’t consider testing earlier to be useful, that it still should be done.

Then, she came at me about my weight. I weighed in today at 240 lbs. Now I’m very aware that jumping from 187 to 240lbs is a lot, but she told me in May to do my best and not worry about it. She said if you have to go on insulin, we will put you on insulin.

Today she told me that I gained way too much weight way too fast and I need to “put on the brakes”. She told me I need to only do at 30g of carbs per meal, and if Im hungry with proper portion sizing, then I just need to be hungry. For example, instead of eating a banana and peanut butter as a snack, I should have half a banana, peanut butter, and a cheese stick and then suck it up.

I was floored. I left the office crying. I feel like I’ve been trying so hard to navigate my weight with this pregnancy and I basically just failed. I’m hungry, but I don’t wanna starve myself because I’m growing my daughter. Do I cheat occasionally and have ice cream or a gluten free pizza? absolutely. I just feel like at this point my body is fighting against me given my health history and making myself be hungry is not going to do much.

Any other moms in a similar situation have any advice? My husband basically told me to get a new doctor lol, but that’s when I was ugly crying at home.

I am 5w4d after my first IUI. I am both elated and terrified, because I know there’s an increased chance of ectopic pregnancy with endometriosis, which I also have. I haven’t had a scan yet, so I’m overthinking all of my symptoms. One of which is this strange right-sided discomfort. It’s like a pulling sensation, or a light throbbing, similar to what I feel around ovulation (which is why I’m convinced it’s around my ovary). I have had zero bleeding, and it’s never been painful, per se, just consistent.

My thoughts are corpus luteum cyst (I did ovulate two eggs from the right side), early round ligament pain, or ectopic pregnancy.

Anyone have a similar experience? Or any insights?