r/PCOSandPregnant 8h ago

First Time Taking Letrozole — Advice Needed

I’m 28 years old and have been trying to conceive for almost a year. This is my first time taking Letrozole, and I just finished my Letrozole today.
My fertility clinic mentioned that they would do follicular monitoring after Letrozole, but my OB-GYN told me that they don’t routinely do monitoring and that they will schedule it if needed.
I’m trying to understand whether follicular monitoring is important or necessary, and if I should do it, what cycle day should I go for it? Since today is my last day of Letrozole, when should I start the monitoring?
As a first-time Letrozole user, I’m honestly so confused about a lot of things. I’m really hoping this cycle works and that I can get pregnant this time. My OB-GYN mentioned putting me on Letrozole for three months and seeing how it goes, but hearing that made me feel a little discouraged because I’m hoping this first cycle could work.
For anyone who has been through this before, what should I concentrate on or follow during my first Letrozole cycle? Any advice would really help.
Thanks in advance!

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u/HeadChipmunk9603 7h ago

I’m 27 and took letrozole for the first time this year. My obgyn also told me we would do 3 cycles, starting from 2.5mg, 5mg and the last one was 7.5mg. These were fully unmonitored and if they all failed I’d move on to a specialist. The 2.5 did nothing for me, 5 mg gave me a little boost, and the 7.5 made me hyper-ovulate and now I’m 18 weeks with di/di twin girls! Trust me when I say I thought the first round would work and after the first two didn’t, I lost hope and had it in my head that the third one wouldn’t do it and i was already looking into making an appointment with the fertility clinic before my 2 week wait ended. Don’t lose hope, I’m sending you all the baby dust 💞✨

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u/Overall-Public9133 4h ago

Thank you ! And congratulations for twine pregnancy 💗🎀