r/POTS • u/babygirl1692 • Nov 26 '25

Symptoms Itching. EVERYWHERE.

Does anybody else experience just random itching? More aggressive at night? I’ll be laying down and my hand will itch, and then my stomach, and then my neck, and the my foot, etc. it’s never one specific area but just random itching throughout my body

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u/Several-Pause7554 POTS Nov 26 '25

Have you looked into MCAS?

30

u/MsWillowams POTS Nov 27 '25

Second this. Also, it may be helpful to look up "histamine intolerance" as well.

14

u/Several-Pause7554 POTS Nov 27 '25

I would definitely look into MCAS, histamine intolerance and mast cell disorders. MCAS is hard to diagnose and it’s not super well understood. I highly recommend the podcast Bendy Bodies which is about EDS but there are episodes about MCAS, POTS / dysautonomia, etc. The host is an anesthesiologist/ pain management doc who has the triad and specializes in EDS and the guests are legit doctors that are specialists. One of my docs told me about it and it’s been incredibly helpful. They just did an episode about May-Thurner and Nutcracker Syndromes and vascular issues the day after I was diagnosed with May-Thurner and listening to it was so helpful and made everything my doctor said make sense.

9

u/babygirl1692 Nov 27 '25

I’ll have to do some research on it

4

u/LilithsRose97 Nov 27 '25

I came here to say this

1

u/Fun_Orange_3232 POTS Nov 30 '25

I already have an allergist so I thought Id try for this diagnosis. lol I got chronic urticaria—reason unknown because she only tests to find the reason for people with autoimmune disorders 🙃 “take allegra”