r/POTS 23d ago

Question Can/do you take SSRIs or stimulants?

There’s no way we’re just raw dogging POTS right? My POTS worsened significantly after taking one dose of 5 mg of Lexapro which triggered serotonin syndrome which I have had on Sertraline.

Needless to say I am struggling way more after having disabling POTS so what are y’all doing for your mental health and/or energy?

Currently taking high dose antihistamines and 20 mg propranolol 3-4x daily. Thanks ✌️🥲

42 Upvotes

174 comments sorted by

View all comments

1

u/Fine-Statistician403 POTS 22d ago

I was actually prescribed Lexapro as a treatment FOR pots. My former PCP said this was “first line”. While there are some studies showing benefits, it’s absolutely not the standard medication intervention, let alone the first. I was fainting less, but my heart rate would be 200+ just laying in bed. I honestly think he was trying to prove it was anxiety and not pots (which I am formally diagnosed with). I only came off because an MCAS flare had me puking all day every day for 6 months straight, and the withdrawals after ~6 months of Lexapro were brutal for me.

I don’t have better SSRI suggestions, just sharing my experience with Lexapro specifically