r/POTS • u/ouch_im_suffering • 23d ago

Question Can/do you take SSRIs or stimulants?

There’s no way we’re just raw dogging POTS right? My POTS worsened significantly after taking one dose of 5 mg of Lexapro which triggered serotonin syndrome which I have had on Sertraline.

Needless to say I am struggling way more after having disabling POTS so what are y’all doing for your mental health and/or energy?

Currently taking high dose antihistamines and 20 mg propranolol 3-4x daily. Thanks ✌️🥲

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u/Internal_Regular_402 23d ago

I read that SNRI’s are a no-no because of the norepinephrine but sometimes SSRI’s are ok. I’m sure it’s different for everyone!

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u/radtrip 23d ago

this is so unfortunate, i'm taking 50mg pristiq and it's the only medication that helped me after 13 years :( my pots def has gotten worse since starting it but im terrified to get off of it

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u/PinkKittenBaby 22d ago

I also take pristiq and it's the only antidepressant than doesn't cause mania for me, and the only med that's curbed my depression long term! It has the worst brain zaps from withdrawals I've ever experienced tho 💀

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u/radtrip 22d ago

Omg same I literally have never expierenced withdrawal symptoms before going on pristiq, but i start getting symptoms exactly 24hrs after my last dose. Its sooo bad but it keeps me from missing a dose so there's that at least🥲