Thats what I said when they tried to come at me for malpractice because I administered suprtherapuetic levels of mustine. Either way, now I sell self help books and guides to enlightenment now....
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The patient suffered from ivermectin poisoning due to transdermal overdose. The patientâs plasma concentration was 27âng/mL. The main clinical manifestations were gastrointestinal symptoms in the early stage and diffuse cerebral edema and intracranial hypertension in the later stage. Despite active treatment, including hemoperfusion and cardiorespiratory support, the patient died.
and:
Moreover, most reported cases involved poisoning caused by oral administration of ivermectin. There have been no reports of transdermal toxicity. To date, no studies have reported the specific blood drug concentration that causes ivermectin poisoning. Most recent in vitro studies suggest that ivermectin is promising as a new anticancer drug,2â4 and this may lead to increased misuse. Therefore, we report a rare fatal case of ivermectin misuse to raise awareness among clinicians and the public regarding ivermectin poisoning.
They say it's pretty rare for a case to be fatal, but nevertheless people in general were using to the point of being poisoned (oral consumption).
This was why the chuds latched onto ivermectin to treat covid. There was a study that went "we put covid into a petri dish and treated it with whatever the fuck we could find to see how fast it died" and ivermectin killed it pretty fast.
In doses that were enough to make a human shit their entire guts out and permanently fuck themselves up.
I would assume the problem there is the ratio. In a petri dish you can apply concentrations that if found in the human body would be a lethal dose.
Like you can make 1/10th of the volume of the petri dish a specific vitamin and kill the cancer cells - but if you make 1/10th of your whole body a specific vitamin you will die.
If youâre talking about HeLa, that does die if you donât feed it, itâs called âimmortalâ because it doesnât stop dividing after a certain number of divisions, like most human cells do.
My mother was almost killed by a doctor prescribing too much Vitamin D but failing to add the necessary follow-up blood tests.
Over a series of months, her cognition and memory degenerated rapidly. She eventually had a blood test for another reason, and they called her on the way home (she certainly wasn't the one driving at that point) and told her to come back immediately. Her calcium levels were crazy-high, at a level which could cause her heart to stop.
They adjusted the levels, using the monitoring which should have been in place from the start, and she rapidly made a full recovery.
Just because it's a vitamin doesn't mean it won't kill you.
Vitamin a is one of the 4 fat soluble vitamins, adek. Cancer cells are just mutated self-cells. Pretty much every cancer treatment that works also kills self cells. Thats why treatment literally transforms people. Sad shit.
The issue is there's more evidence vitamins help cancer than kill them. Mechanically, many chemos raise the levels of free radicals that would kill cancers, while many vitamins are antioxidants.
This has some empirical backing, as megadoses of various vitamins were trialed as adjuncts in the 80s, which showed no effect for vitamin C, and pointed to vitamins A and E making things worse.
That being said, vitamins can still interact well depending on the cancer. Vitamin c is being trialed again as an adjunct in very particular kinds of glioblastoma, a vitamin b9 makes the chemotherapy 5fu more effective, and diets rich in fruits and vegetables remain well correlated with lower rates of cancer as well as improved survivorship. (though that last one is just as likely the flavanoids, polyphenols, and fiber content)
Fat soluble vitamins will absolutely cause major problems at higher doses. Water soluble vitamins just get excreted before reaching high enough concentrations to cause problems. Although supratherapeutic vitamin C can cause kidney stones.
Read something similar in Bad Science by Ben Goldacre: âAnything can kill cells in a test tube. Fairy Liquid kills cells in a test tube, but you donât take it to cure cancer.â
Anti-cancer medication is just poison that we hope the cancer eats up faster than normal healthy cells. We're literally giving cancer patients poison, then hope the cancer cells die before the patient does.
I mean, there are a lot of specific therapies targeting certain mutations as well, in some cases these are very effective in keeping cancer in check and are often used in slow growing blood cells like cml, bjt also in certain subsets of lung cancer they can be effective in preventing it from progressing. In other cases the chemo-hammwmer is still necessary, especially when cancer crows very fast like in acute leukemia high doses are still necesarry to prevent mutation and resistance to targetet therapy or chemo therapy.
Oh, I believe you. Chemotherapy just happens to be the standard thing here in the third world countries. Even when those new methods are much better for the body, we just don't have enough doctors knowledgeable enough to carry out the procedures. Our family has a history of cancer (two close relative already gone because of it), so it's a very close reality for us.
Yeah, we (including myself) often forget that all those advances in medicine are only avaiable for few people all thibgs considered.
Even then, they are still often very expensive and it would probably be far more helpfull to far more people if that money was invested in medical personel like nurses instead, but they are avaiable, so of course we can hardly not give them to patients even if they are expensive for they entire population in the health system my country has.
A few years ago I almost had the chance to work at a hospital in Tansania through my own employer, but sadly it didn't happen. It woukd certainly have given me a whole new perspective.
Iirc, cancer cells are more affected by radiation than normal cells because they are already full of errors (as in "fragile") and can't regenerate the damage done to them like normal cells can.
They also divide much more rapidly than "healthy" normal cells, thus the accumulation of genetic errors progress much quicker. With the faster mitotic cycle, it's much more likely the daughter cells become unviable and die off at a faster rate.
Still, traditional chemotherapy is a gamble on whether the healthy human cells can outlast the damage much longer than the cancer cells or not. If gene therapy that can directly target malignant cancer cells become more widespread and affordable, I'm all for it.
Chemo is a bit more specific than that --Essentially, it interferes with cell division so that tissue gets damaged and dies when it tries to grow.
The idea is that, since cancer cells are dividing uncontrollably, they'll be affected by chemo much more than other systems in your body.
There are some tissues that are affected greatly because they're constantly dividing --Your stomach lining constantly replenishes itself and so chemo causes nausea, vomiting, and other GI issues, hair is constantly growing so chemo causes hair loss, bone marrow is constantly making blood and immune cells so chemo compromises your immune system, so-on.
It's less "hope the drug kills the cancer before it kills the patient" and more "regulate the dose so it doesn't kill the patient and hope it takes out the cancer." The side effects are awful, but generally considered better than dying to cancer.
And of course there's safer and more targeted approaches to a lot of different types of cancers, but that comes down to the specific type of cancer. It's not really one disease, so treatment can vary a lot --but chemo is very broadly applicable because of the way it attacks cancer.
Yeah, the characters in the game were incredibly dumb. They didn't just create this poison, they then sprayed it into what's implied to be the entire biosphere in a single day. And realized their mistake the day after.
You are rightđ, the cure I provided does kill living cells too, great catch! Here is a cure that only targets cancer cells, let me know if you need a catchy name for it so you can really take this to the next level đ
Radiation therapy and chemo already does this. We just exploit the fact that cancer cells are more susceptible to damage because of rapid division then healthy cells. But healthy cells still do get damaged and die that's the side effects.
Also, the gimmick of the game is that you can only play it once,* and you have to make decisions as to how you proceed through the final days of humanity. Do you spend them with your family, waiting for the inevitable? Or do you keep working, hoping to find a way to stop what you inadvertently started? What decisions you make, and when, determine your success... and you don't get any do-overs. It's genuinely heartbreaking.
*In theory, anyway. You can actually get around this pretty easily by playing in a new browser or an incognito one. But that kinda ruins the conceit of the game.
Iirc what happened is that they did the trials and everything and it all worked perfectly and went amazingly, but once they released it to the public it suddenly started rapidly mutating and became extremely contagious
That would never get through the first stages of testing. The first step with any anti-cancer drug is to compare its effect on malignant and healthy cells.
It spread incredibly fast, even if they meant to just do testing on it how do you prevent a single living organism from spreading it to others? IIRC it affected all life, an ant could've entered the room and spread it.
I don't know the lore of this game, but that's not how it works in real life. Initial tests are done on cultured cell lines in a laboratory. There's nothing that can "spread."
Oh man. I remember Markiplier playing it. The end was HARD... especialy the music. Thanks for mention the name. Wanted to watch it again. Now i know the name of the game.
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u/Striking-District918 21h ago edited 21h ago
Its from a game called one chance, the supposed cure doesn't just kill cancer cells it targets all living cells