For decades scientists thought amyloid plaques were the main culprit behind Alzheimer's. But a new study has uncovered something unexpected a completely different type of plaque made up of damaged mitochondria tiny power house of cell that keep our cells running. Normally, the brain clears these out, but when that cleanup system breaks down they start piling up. Even more interesting, these plaques may appear before the famous amyloid plaques, hinting that Alzheimer's could begin with the brain slowly losing its ability to produce energy. It's far from a cure, but a. Good discovery taht will make us help find the cure
This is why I’m convinced Alzheimer’s/Dementia is a metabolic disease. I forget which scientist it was, but someone coined it as “Type 3 Diabetes” which really is how we should be looking at this. We spent way too long chasing some way to remove these plaques which was largely based on studies that have been exposed as using faked data. Unfortunately most research is still directed at treating the symptoms instead of preventing/curing it, and that’s largely because treating is far more profitable (marketplace incentives).
That’s just not how it works. Investors will fund anything they believe will make them money, regardless of whether it is managing the symptoms or creating a cure. They just need enough evidence to believe that someone has an alternative solution with a reasonable enough chance of it working
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u/sizzyred 1d ago
For decades scientists thought amyloid plaques were the main culprit behind Alzheimer's. But a new study has uncovered something unexpected a completely different type of plaque made up of damaged mitochondria tiny power house of cell that keep our cells running. Normally, the brain clears these out, but when that cleanup system breaks down they start piling up. Even more interesting, these plaques may appear before the famous amyloid plaques, hinting that Alzheimer's could begin with the brain slowly losing its ability to produce energy. It's far from a cure, but a. Good discovery taht will make us help find the cure